Synthetic BAs and Derivatives

Since the hormonal properties of bile acids was established over 20 years ago, bile acids are now the focus of new drugs to treat metabolic and neurodegenerative diseases.

ICE Pharma can support drug discovery activities by providing bile acid building blocks for medicinal chemistry activities. We have an extensive range of 6-alphe ethyl CDCA intermediates and final product markers. Please enquire for bespoke bile acid derivatives our skilled chemistry team are available to assist.

ICE002 Methyl cholate

ICE083 diketo-obeticholic acid

ICE084 Obeticholic acid

ICE153 diketo-allo-obeticholic acid

ICE156 6-epi-diketo-allo-obeticholic acid

ICE159 6-epi-diketo-obeticholic acid

ICE160 7-epi-iso-obeticholic acid

ICE161 7-epi-obeticholic acid

ICE162 iso-obeticholic acid

ICE168 6-epi-obeticholic acid

ICE175 7-keto-obeticholic acid

ICE176 7-keto-iso-obeticholic acid

ICE183 6-epi-iso-obeticholic acid

ICE185 Obeticholic acid methyl ester

ICE189 sodium 6a-ethyl-3a,7a-dihydroxy-23-sulfooxy-5b-24-nor-cholane

ICE292 6-epi-7-keto-obeticholic acid

ICE313 Obeticholic acid dimer

ICE418 Sodium 6a-ethyl-3a-hydroxy-7-keto-23-sulfooxy-5b-24-nor-cholane

ICE420 6-epi-3-keto-obeticholic acid

ICE421 6-epi-7-keto-iso-obeticholic acid

ICE487 6-epi-7-epi-obeticholic acid

ICE488 6-epi-7-epi-iso-obeticholic acid

ICE605 22-hydroxy-3,7-diketo-23,24-bisnor-5b-cholane

ICE650 6-epi-7-keto-allo-obeticholic acid

ICE652 7-keto-allo-obeticholic acid