Bile alcohols and bile acids show remarkable structural diversity across animal species. No other class of small molecules in vertebrates exhibits such a variety of chemical structures. Structural variation occurs in the steroid nucleus in several ways, A/B ring juncture stereochemistry, sites of hydroxy or oxo groups, and orientation of hydroxyl groups. Structural variation in the side chain includes the length of the side chain, the presence and orientation of hydroxy groups, the presence of unsaturation, the stereochemistry of the C-25 carbon atom, and the site of the carboxyl group.
ICE Pharma offer synthetic bile acids and bile salts that are species specific, these include ranges for rodents, pigs and dogs. Please enquire if you need other species-specific bile acids.